The Accufy NGS tagging library preparation and Accufy NGS target enrichment technologies revolutionize the MRD analysis on liquid biopsy samples via NGS in that they features the greatest sensitivity, short sample prep time and preservation of both epigenetic and genetic information from the patient DNA molecules. They can be coupled with existing NGS sample prep or target enrichment technologies. They can also be used as a turnkey solution for multiomic NGS. The potential applications of the technologies are many.
Example: EGFR exon 19 deletions
Example: KRAS (absence of mutations in codons 12 and 13)
Example:BRCA1, BRCA2 alterations
Example: (HER2) amplification
Example:FGFR2 fusions
Example:NTRK1/2/3 fusions
Example: NDRG4 (N-myc downstream-regulated gene 4)
Example: BMP3 (bone morphogenetic protein 3)
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